Frequently Asked Questions

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We’re very sorry, but we do not sell directly to individuals.

However, you can browse our list of retailers to find a nearby store or an online shop that carries our products.

You can find a tone of resources on our different product pages, and also in our resource library that you can access by clicking on this link.

Sure!

If you are a distributor we will be more than glad to provide you with brochures, videos or point of sales displays to promote our products.

If you are a beekeeping school, please also write to us ad we can provide educational resources such as guides to help beekeepers navigate in the world of varroa mites, bee nutrition and fight against the asian hornet.

We’d be delighted!

You can reach out to Séverine Délot, our Communications Manager, at +33 1 69 18 84 80 or via email at severine.delot@vetopharma.com.

You can check the list of our retailers by clicking here.

There are no temperature constraints during treatment with Apivar.

However, when storing the product for extended periods, avoid exposing it to very high temperatures (above 30°C or 86°F) or very low temperatures, such as frost.

Apivar contains amitraz, a synthetic insecticide and acaricide that functions as a neurotoxin. Disposal methods may vary depending on your country. We recommend consulting your local regulations to ensure the strips are disposed of safely and in an environmentally responsible manner.

• Position the strips correctly: Ensure the strips are placed in the brood center to maximize contact between bees and the strips. Remember: contact = effectiveness!
• Feed your bees during treatment: Feeding stimulates colony activity, increasing the likelihood of bees contacting the strips.
• Scrape and reposition the strips: At mid-treatment, remove any wax or propolis from the strips and reposition them in the brood center.
• Leave strips for the full duration: When brood is present, keep the strips in the hive for the maximum duration allowed as specified on the label.

• Act early: Do not wait for infestation levels to reach damaging thresholds before treating your colonies.
• Renew brood combs regularly: Replace 30% of your brood combs each year to maintain healthy colonies.
• Rotate treatments: Rotate active ingredients (ideally using different molecules within the same year) to target mites through various mechanisms and reduce the risk of resistance

Yes, Apivar® 2.0 has received federal approval from the United States Environmental Protection Agency (EPA), confirming it meets all necessary safety and effectiveness criteria.

State-level approvals are handled separately, as each state has its own regulatory process. Updates on these registrations will be shared through the provided link.

The timeline for state approvals can differ, ranging from several weeks to a few months (or even years!). We’ll continue to post updates on our website as new state registrations are finalized.

Apivar® 2.0 is legally permitted for use in the U.S., as long as it is applied according to the EPA’s guidelines and any other applicable regulations.

The list of distributors will be available soon at this link: click here.

We’ve scheduled the first production runs for this spring to ensure the product is delivered to the U.S. in time for the Varroa mite treatment season this summer. We’ll keep you updated as soon as it becomes available at beekeeping retailers. Make sure to subscribe to our newsletter to stay informed!

We are actively working on obtaining registration for Apivar® 2.0 in California. However, due to the state’s unique regulatory process and more stringent requirements, approval may take longer than in other regions. At this time, we cannot provide a definitive timeline. We will continue to post updates on our website and notify our customers as soon as Apivar® 2.0 is officially registered in California. In the meantime, California beekeepers can continue using the original Apivar, as both versions will remain available concurrently in the U.S. for a transitional period.

Our team is actively working to expand the registration of Apivar® 2.0 internationally. However, each country has its own specific regulatory framework and approval process that we must carefully follow. In regions such as the European Union, the United Kingdom, and several others, Apivar® 2.0 is classified as a veterinary medicine, which often involves more detailed and time-consuming procedures.

We’ll continue to share updates as we receive new information regarding product availability and prescription requirements in various countries.

To start, please note that Apivar® 2.0 and Apivar are two different products, registered under two separate product registrations. The composition and appearance of the strips are not the same.

In the long run, yes, Apivar® 2.0 will replace Apivar, as its benefits will outperform those of the regular Apivar. However, since some states take longer to register a product (for instance, California), both products will co-exist on the market for a while.

Apivar® 2.0 has been specifically formulated to act more quickly within the bee colony, achieving a rapid reduction in mite levels within the first few weeks of treatment. We've also improved the hanging system of the strips and developed a design that can be adjusted to fit most hive types, whether they have short or tall frames.

Additionally, the directions for use have been enhanced, now supported by data that allow for "no withholding period" during honey flow. This means you can place your honey supers on the hive immediately after removing the strips. We've also refined the treatment duration based on our experience with mite control: 6 to 10 weeks, with the 10-week option being more suitable when brood is still present in the colony. This extended duration helps target emerging mites across multiple brood cycles, ensuring a healthier, cleaner colony.

The previous version of Apivar contained 3.33% amitraz, while Apivar 2.0 contains 3.00%. This slight difference does not imply that the product is less effective. On the contrary, with the development of Apivar 2.0, as well as Amiflex®, the release of amitraz from these new formulations was accelerated without increasing the dosage. This was achieved by optimizing the composition of other materials (carriers) in the treatment formulations. Apivar 2.0 has been specifically formulated to ensure a more efficient release of the active ingredient, particularly during the first weeks of treatment.

No, Apivar 2.0 is an extruded plastic strip. This means that amitraz is blended with plastic powder and other ingredients, then heated to a specific temperature and processed through a machine to form the strips. If the appearance differs from the original Apivar, it's due to differences in the ingredients used in the formulation.

We do not disclose the specific names of the other ingredients, as they are part of a proprietary formulation. However, we can confirm that the formulation includes only two additional ingredients (compared to the original Apivar, which contained only amitraz and the plastic of the strips). These additional components have been carefully selected to support the controlled release of amitraz and to enhance its stability over time. All two have been thoroughly evaluated and approved for use in honey bee colonies. Additionally, the final product has undergone rigorous testing to ensure it is non-toxic to colonies and does not leave harmful residues in the hive

No, the absence of brood is not a requirement for using Apivar® 2.0. If there is no brood in the hive, the strips can be removed after 6 weeks of treatment. However, if brood is present, we recommend keeping the strips in place for the full treatment duration of up to 10 weeks to effectively target mites emerging with new brood cycles.

The Apivar® 2.0 strip is a contact-based delivery system, similar to the original Apivar. The active ingredient, amitraz, is released through direct contact between the bees and the strips, and gradually spreads throughout the colony as bees interact and come into physical contact with one another.

Apivar® 2.0 has undergone thorough field testing across various apiaries in France, using both Langstroth and Dadant hives. These trials have assessed its efficacy against varroa mites, safety for bees, residue levels in hive products, and product stability over time. We are also currently conducting studies in other countries for registration purposes.

Apivar® 2.0 is available in packs of 4, 12, and 60 strips. Since you need 1 strip for every 5 frames of bees, this equates to 2 strips per brood chamber - or 4 strips for a double brood chamber.

Unopened Apivar® 2.0 packs have a shelf life of 24 months from the date of manufacture, as stated on the label. This duration is valid only when the product is stored correctly. For best results and to maintain effectiveness, keep unopened packs in a cool, dry place, protected from direct sunlight

Once opened, the strips should be used immediately, as indicated on the label.

The EPA label recommends to wrap used strips in newspaper and place in the trash. It is important to avoid contaminating water sources. For specific disposal guidelines in your area, consult your local waste management authority or review regional pesticide disposal regulations.

Before a Varroa treatment is authorized for use in honey bee colonies, it must undergo rigorous testing to confirm that residues in honey or beeswax after treatment remain below the pre-defined thresholds that are considered safe.

This does not mean an authorized treatment can be used during honey flow, while honey supers are in place. Even low residue levels in honey supers can risk honey contamination. Like most approved Varroa control products, Apivar® 2.0 is intended for use outside of the honey flow period only.

However, one key advantage of Apivar® 2.0 compared with Apivar is that it needs no withdrawal period. This means beekeepers can safely add honey supers to the hive immediately after the Apivar 2.0 strips have been removed at the end of treatment.

We recommend a maximum of two Apivar® 2.0 treatments per year. Ideally, the active ingredients of varroa treatments should be rotated throughout the year to target varroa mites with different substances. This approach helps preserve the long-term effectiveness of all varroa mite control options.

Amitraz has been widely used for Varroa mite control across the globe for many years. Research has consistently shown that honey bees can tolerate much higher levels of amitraz than what is needed to effectively eliminate Varroa mites.

Recent findings also suggest that the common residues of amitraz metabolites found in beeswax do not adversely affect key indicators of bee health, including drone sperm viability, queen body mass, egg-laying patterns, or the emergence mass of worker bees.¹

In our own studies concerning the treatment‘s safety for bees, conducted as part of the Apivar 2.0 registration process, no harmful effects on worker bee survival or the amount of brood present in the colonies were observed following the treatment.

This doesn’t mean that amitraz is completely harmless to bees - but it highlights the importance of using properly formulated and approved treatments like Apivar® 2.0, Amiflex® and Apivar®. These products have been precisely developed to ensure efficacy against mites while minimizing risk to the colony.

1 - McAfee, Alison, et al. “Honey bee queen health is unaffected by contact exposure to pesticides commonly found in beeswax.” Scientific Reports 11.1 (2021): 1–12.

We firmly believe that amitraz remains a highly effective tool in the fight against Varroa mites. Its gentle action on bees and reliability as a varroa mite treatment - regardless of ambient temperature - make it a user-friendly and well-tolerated treatment option, provided it is used in compliance with the product label.

However, it's every beekeeper's responsibility to use mite treatments wisely. Rotating active ingredients throughout the year - and thereby alternating different active ingredients / substances - is key for a sustainable varroa mite management. Recent studies are showing that even mite populations resistant to amitraz may regain sensitivity, if they are treated with an alternative active ingredient in the meantime (such as oxalic acid). Similar patterns have been observed in other species such as cattle ticks, where resistance tends to reset seasonally.

For this reason, we strongly encourage rotating varroa mite treatments and alternating active ingredients to help preserve the long-term effectiveness of amitraz-based products.

The formulation, packaging, and conditions of use of Amiflex and Amiflex 2.0 in the United States are identical. The only distinction is that the RUP (Restricted Use Pesticide) license requirement, previously applicable to Amiflex, is no longer required for Amiflex 2.0.

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Our team is working diligently to register Amiflex in more countries, but it’s important to note that each country has its own unique requirements and regulatory processes that we must adhere to. In the European Union and many other countries, Amiflex is considered a veterinary medicine, which can result in more lengthy and complex registration procedures.

We will keep our customers updated as we receive more information regarding availability and prescription status in different countries.

Amiflex/Amiflex 2.0 is intended to complement the varroa treatment toolbox of beekeepers and is not meant to replace regular slow-release treatments. Veto-pharma supports an integrated pest management (IPM) approach to varroa mite control.

Slow-release varroa mite treatments are important to manage mite infestations in the long term. However, flash treatments with Amiflex/Amiflex 2.0 offer additional benefits, such as lowering the mite infestation during the season (in-between honey flows) and providing a quick knock-down effect to prevent an excessive infestation before the late-summer or fall treatment. This can help to prepare honey bee colonies for a successful overwintering and optimize the effectiveness of the long action treatments.

Amiflex has undergone some tests, demonstrating its effectiveness in reducing varroa mite infestations in bee colonies, with efficacy rates of up to 99% in brood-free colonies.¹ It can also be used in colonies with brood, with efficacy around 56% for a single 7-day application, to 83% with two consecutive 7-day applications (with a 7-day break in between).^2,3 Amiflex/Amiflex 2.0 can also be applied in-between honey flows or right before a slow-release treatment to help reduce mite infestations, as long as honey supers are not on the hives.

In case of high infestation, we recommend making two consecutive applications of Amiflex/Amiflex 2.0, with a 7-day break in between each application. Please refer to product labeling for complete instructions. Please note that, in Canada, a maximum of two applications per year is permitted.

¹ Testapi. (2021). Assessment of effects of a single application of multiple doses of “FLASH” formulation on broodless honeybee colonies in Dadant and double Langstroth shaped hives and associated efficacy against Varroa destructor. GLP Study No. 507-2021.

² Testapi. (2021). Assessment of effects of one or two applications of “FLASH” formulation on honeybee colonies in Dadant shaped hives and associated efficacy against Varroa destructor. GLP Study No. 514-2021.

³ Testapi. (2021). Assessment of effects of one or two applications of “FLASH” formulation on honeybee colonies in double Langstroth shaped hives and associated efficacy against Varroa destructor. GLP Study No. 552-2021.

The Amiflex/Amiflex 2.0 gel is a contact delivery system for varroa mite control, similar to other treatments like Apivar. The gel’s active ingredient, amitraz, is released through contact with the bees and gradually spreads throughout the colony when bees interact or get in physical contact with each other.

A pack of Amiflex/Amiflex 2.0 contains 10 cartridges or 120ml of gel each.

The number of colonies that you can treat with one Amiflex/Amiflex 2.0 pack depends on the hive type (single or double):

• Single brood chambers will require 2 doses of 3ml of gel = you can treat up to 200 colonies with one pack.
• Double brood chambers will require 4 doses of 3ml of gel (two doses per brood box) = you can treat up to 100 colonies with one pack.

Furthermore, we are committed to making Amiflex/Amiflex 2.0 available in more countries and using a standardized dosing gun is a step towards that goal. That’s why we opted for milliliters as the unit of measurement.

That’s an excellent question, and we have a great answer. Amiflex/Amiflex 2.0 is accompanied by a dosing gun that ensures accurate dosing. With this dosing gun, there’s no need to worry about different metrics, whether they are milliliters or ounces. Simply pull the trigger twice per brood box, and you’re done!

It is not possible to use any other application tool with Amiflex/Amiflex 2.0. The dispensing gun specially designed for Amiflex/Amiflex 2.0 ensures the precise and consistent dosage required for each treatment. Using any other application tool may result in inconsistent dosage, which may compromise the effectiveness and safety of the treatment.

While we do not have plans for smaller packaging as of now, we will certainly keep everyone updated if that changes in the future.

Please also note that each pack of Amiflex/Amiflex 2.0 is suitable for treating 100 to 200 hives (depending on the hive type) making it a viable option for sideliner beekeepers as well.

Amiflex/Amiflex 2.0 in its current packaging of 10 cartridges, which was designed to provide commercial beekeepers with a legal treatment solution to manage varroa mites in between honey flows.

It’s important to note that the shelf life is only valid if the pack has been stored properly. To ensure the product’s efficacy and longevity, it’s recommended to store unopened cartridges in their original packaging in a cool, dry area, away from direct sunlight.

The shelf life of an unopened Amiflex/Amiflex 2.0 pack is 24 months after manufacturing, as indicated on the label.

After initiating the first use of a cartridge, it is important to immediately use the Amiflex/Amiflex 2.0 gel in this cartridge and discard any remaining unused product.

Store unopened cartridges in the original aluminum bag, in a cool, dry area away from direct sunlight, as indicated on the label.

For USA users: To avoid waste, use all material in this container by application according to label directions. If wastes cannot be avoided, offer remaining product and used wooden supports to a waste disposal facility or pesticide disposal program (often such programs are run by state or local governments or by industry).Nonrefillable container. Do not reuse or refill this container.

Dispose of in a sanitary landfill. Do not burn unless allowed by state and local ordinances.

For Canadian users: Dispose of packaging and used syringes and supports in accordance with provincial or territorial requirements. For information on disposal of unused, unwanted product, contact the registrant or the provincial or territorial regulatory agency. Contact the registrant and the provincial or territorial regulatory agency in case of a spill, and for clean-up of spills.

It is important to avoid contaminating water, food or feed, and to not reuse or refill empty syringes.

Additionally, this approach helps prevent the presence of small quantities of amitraz inside the hive after treatment. This is beneficial for maintaining the sensitivity of varroa mites towards amitraz.

By using the wooden supports, you can easily remove any leftover gel at the end of the 7-day treatment, and then place the honey supers back on the hive right away, without any additional waiting period.

The wooden supports are intended to help you remove any leftover gel from the hive once the treatment is complete. Applying the gel directly to the top bars can make it difficult to remove the gel that remains after the treatment period, and would have led to a withdrawal period before being able to place honey supers back on the hive.

Furthermore, there is no withdrawal period for Amiflex/Amiflex 2.0, which means that beekeepers can place the honey supers back on the hives right after removing the product at the end of the treatment.

The short treatment period of Amiflex/Amiflex 2.0 (7 days) allows for great flexibility of the treatment timing: before, in-between, or right after a honey flow.

However, this does not mean that mite treatments can be used during honey flow when honey supers are on, as there is still a risk of residues being left behind. Thus, like most other authorized varroa mite treatments, Amiflex/Amiflex 2.0 should only be used outside of honey flow, in any season when the supers are not placed on the hive and as long as bees are active.

When registering a varroa treatment, we have to test it to ensure that it doesn’t leave high amounts of residues in honey or wax, which can affect the safety of the consumers, when used according to the label directions.

Our laboratory experiments have shown that different formulations, even with the same concentration of amitraz, produce varying results depending on the excipients used in the formulation and types of formulation. This is why the use of illegal treatments does not provide constant results in terms of efficacy or toxicity for bees, and why it’s crucial to only rely on registered treatments that have been tested and approved.

It is important to keep in mind that the concentration of the active ingredient is not the only factor that determines treatment efficacy. The formulation also relies on other ingredients, which act on the release of the active ingredient.

Despite the lower concentration, Amiflex/Amiflex 2.0 has been demonstrated to be effective at reducing varroa mite infestations in bee colonies when used according to the label directions. The product’s gel formulation has been specifically developed for short-term release of amitraz, allowing high flexibility in timing varroa treatments during the season during the 7-day treatment period.

Amiflex/Amiflex 2.0 should be applied as a supportive treatment to efficiently reduce mite infestation during the season (before, in-between, or right after honey flows). It provides efficient support in varroa mite control, in addition to the main (end-of-season) varroa treatment.

You can use Amiflex/Amiflex 2.0 in two consecutive applications with a 7-day break in between. It will make a total of 21 days and will cover a full cycle of worker bee brood.

The use of authorized treatments such as Amiflex®/Amiflex® 2.0 and Apivar®, which have been carefully developed and dosed appropriately, is crucial to treat honey bee colonies safely against varroa mites with amitraz-based miticides, when used according to the label directions.

When used according to label directions, Amiflex/Amiflex 2.0 does not harm the bees, beekeepers, or hive products thanks to its components quality and specific dosage.

A recent study has found that main amitraz metabolite commonly found in beeswax do not negatively affect traits such as sperm viability in drones, queen mass, egg laying pattern, or emergence mass of daughter worker bees.*

* McAfee, Alison, et al. “Honey bee queen health is unaffected by contact exposure to pesticides commonly found in beeswax.” Scientific Reports 11.1 (2021): 1-12.)

Of course, the responsible use of amitraz-based varroa treatments is necessary to retain treatment efficacy. Amiflex/Amiflex 2.0 represents a different, more flexible option to use amitraz in varroa control, not a “second Apivar”. We therefore recommend alternating active ingredients in varroa treatments and build an integrated pest management strategy in order to preserve the efficacy of amitraz-based products.

Why amitraz-based? Because amitraz is independent from ambient temperatures when used as a miticide during the season. Unlike some of the flash or short-term treatments based on organic compounds, amitraz release is not associated with temperature-dependent evaporation.

Before the authorization of Amiflex/Amiflex 2.0, no legal amitraz-based flash treatment against varroa mites was available. Especially amongst sideliner and commercial beekeepers, the need for a flexible amitraz-based treatment that can be used on short notice in between honey flows or as a quick knock-down treatment before slow-release treatments became apparent over the years.

It is our recommendation rotating varroa treatments with different active ingredients for sustainable varroa control. Specifically, we do not recommend using amitraz-based treatments only during the same season, from spring until fall.

You can view the list of our distributors by clicking here.

To reliably monitor infestations, colonies should be tested at least four times a year:

Early spring
Early detection helps plan and assess the need for a spring treatment before adding honey supers. A second check after the treatment will confirm a reduction in infestation levels.

Between honey flows
This check helps detect any significant reinfestation and decide if spot treatment is required.

Late July / August
This is a key time to select the most appropriate late-season treatment based on infestation levels. It’s critical to compare pre- and post-treatment infestation rates to accurately measure treatment effectiveness.

September / October
Ensure the autumn treatment was effective and determine if an additional winter treatment (when broodless) or early spring treatment is needed.

When temperatures are too low, we recommend using sticky board monitoring instead. This avoids opening the hive and breaking the cluster, ensuring the bees remain undisturbed during cold weather.

• ≤ 10 hives: All hives
• ≤ 20 hives: 6 to 10 colonies
• > 20 hives: At least 25% (minimum of 8 colonies)

We recommend a sample of 300 bees (upper mark inside the white basket) for better representation.

However, if the hive population is low, you can use a sample of 200 bees (lower mark inside the white basket).

A 2023 study on bumble bees observed that queens are more sensitive to CO2 exposure than worker bees.

The research states:

To calculate the infestation percentage, divide the number of mites counted using the Varroa EasyCheck by:

• 3 (for a sample of 300 bees),
• 2 (for a sample of 200 bees),
• or adjust according to your sample size.

This gives you the number of mites per 100 bees.Example: For a sample of 300 bees, you find 15 mites:
15 ÷ 3 = 5% infestation (too high!).

• Early spring: ≤ 1%
• Between honey flows: ≤ 2%
• End of season (July – August, before treatment): ≤ 3%
• Late autumn – winter (after end-of-season treatment): ≤ 1%

Yes, provided you filter it thoroughly to remove the mites. You can reuse it for up to ten tests.

No, this is not possible because it tends to clump due to moisture and potential bee excretions during shaking.

It depends on how much CO2 you use per injection, but on average, a 16-gram cartridge can sample between 3 and 5 hives.

You need to purchase 16-gram threaded CO2 cartridges (with screw threads). These can be found at some beekeeping supply stores, in recreational shops (for bike pumps), and very easily online.

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Unfortunately, we are unable to sell directly to individual customers. However, our network of distributors can meet your needs, either online or in-store.

To find the list of retailers, click here.

It’s very simple!

Send us an email at order@vetopharma.com explaining your request.

Our sales team will guide you through the steps to become a VespaCatch distributor.

• At height: Hang the trap from a branch, 1.5 to 3 meters (5 to 10 feet) above the ground.
• Near hive entrances: Place it on the ground or hang it next to the hive (some beekeepers attach it to the hive’s entrance guard).

• 2 hornets per hive: 1 trap for 2 hives.
• 3 to 5 hornets per hive: 1 trap per hive.
• More than 5 hornets per hive: 3 traps for 2 hives.

VespaCatch traps are highly durable!

We have improved the quality of the plastic in recent years to ensure they withstand weather conditions and sunlight, offering a long lifespan.

The VespaCatch attractant is made from natural plant extracts to lure Asian hornets and denatured alcohol to deter bees. It is an insecticide-free product that works through its olfactory properties.

• For the VespaCatch Original: Replace the attractant when the trap is full or every 3 weeks.
• For the VespaCatch Select: Refresh the attractant every 3 weeks to maintain its olfactory effectiveness.

Yes, it’s possible to use homemade recipes, such as a mix of beer, syrup, and white wine. However, these homemade attractants are usually less selective and may attract other insects.

The VespaCatch attractant is specifically designed to maximize the capture of Asian hornets while minimizing non-target captures.

Not necessarily. We advise against washing them with soap, as it could reduce their effectiveness. If needed, simply rinse them with water.

Additionally, leave one hornet (dead or alive) in the trap when replacing the attractant to help lure more hornets.

• Check the location: Traps should be placed in areas with high hornet activity, such as near hives, water sources, or hedges.
• Verify the attractant: Ensure it is properly set up and still effective. Keep in mind that attractants can be less effective below 59°F (15°C).
• Move the trap: If captures remain low, try relocating it to a more active area.